日誌
吃太辣致癌，治療癌症也和消炎有關(建議多喝優酪乳、豆漿、桑葚藍莓蔓越莓果汁、茶) . ...
故事：
愛吃麻辣燙的一家三口得了食道癌，一死兩晚期
南京一位23歲的女白領被查出胃癌晚期，這名白領經常忽視一日三餐，麻辣燙、燒烤常常被當成主食
「麻辣燙」當飯吃...便血腹痛 16歲少女罹患結腸癌
TRPV1 channel, known as a capsaicin receptor, was recently documented to be expressed on the cells of the immune system but also aberrantly expressed in the several tumor types.
TRPV1 通道，被稱為辣椒素受體，最近被證明在免疫系統的細胞上表達，但也在幾種腫瘤類型中異常表達。
It is activated by heat, protons, proinflammatory cytokines, and associated with pain and inflammation.
它被熱、質子、促炎細胞因子激活，並與疼痛和炎症有關。
In recent years, TRPV1 was discovered to play essential roles in cancer tumorigenesis and development, as TRPV1 expression levels are altered in numerous cancer cell types. Several investigations have discovered direct associations between TRPV1 and cancer cell proliferation, cell death, and metastasis.
近年來，人們發現 TRPV1 在癌症的發生和發展中發揮著重要作用，因為TRPV1的表達水平在多種癌細胞類型中發生了改變。多項研究發現 TRPV1 與癌細胞增殖、細胞死亡和轉移之間存在直接關聯。
TRPV1 and TRPV4 proteins were found to be upregulated in ESCC(esophageal squamous cell carcinoma) cells.
發現 TRPV1 和 TRPV4 蛋白在 ESCC（食管鱗狀細胞癌）細胞中上調。
TRPV1, nociceptor, causes pain hypersensitivity associated with neuropathic pain, peripheral inflammation [43] and cancer cell growth and metastasis (Table 2).
TRPV1，傷害感受器，引起與神經性疼痛、外周炎症 [43] 和癌細胞生長和轉移相關的疼痛超敏反應（表2）。[46]. Therefore, nociceptive TRP channels potentiate initiation of cancer progression and promote cancer development and malignancy.
因此，傷害性 TRP 通道增強了癌症進展的啟動並促進了癌症的發展和惡性腫瘤。
The capsaicin receptor, transient receptor potential vanilloid type 1 ion channel (TRPV1),has been identified as a polymodal transducer molecule on a sub-set of primary sensory neurons which responds to various stimuli including noxious heat (> -42 degrees C), protons and vanilloids such as capsaicin, the hot ingredient of chilli peppers.
辣椒素受體，瞬態受體電位香草素 1 型離子通道 (TRPV1)，已被確定為初級感覺神經元子集上的多峰換能器分子，可響應各種刺激，包括有害熱 (> -42 攝氏度)、質子 和類香草素，如辣椒素，辣椒的辣味成分。
Our data, for the first time, showed that the overactivation of TRPV1 and TRPV4 promoted the proliferation and/or migration of ESCC cells.
我們的數據首次表明，TRPV1 和 TRPV4 的過度激活促進了 ESCC 細胞的增殖和/或遷移。
In the gastrointestinal tract, TRPV1 is mainly distributed in the submucosal nerve plexus of the intestinal tract, myenteric nerve plexus
在胃腸道中，TRPV1主要分佈於腸道黏膜下神經叢、腸肌間神經叢(我過世的父親嗜吃辣被醫生切除腸癌)
Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain
腸躁症中表達辣椒素受體 TRPV1 的感覺纖維增加及其與腹痛的相關性
Conclusions: Increased TRPV1 nerve fibres are observed in IBS, together with a low-grade inflammatory response.
結論：在 IBS(腸躁症) 中觀察到 TRPV1 神經纖維增加，以及低度炎症反應。
總結以上：
由於辣椒素受體造成發炎及癌症
因此治療癌症也和消炎有關
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消炎治療癌症
乳酸菌減弱胰臟癌的進展(西藥治療胰臟癌應該可以用消炎藥+干擾素)
含硫食物的硫引起癌細胞死亡(非類固醇抗炎藥（NSAIDs）好像也有含硫成份的抗炎藥)
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消化不良+胃食道逆流的聯想(建議多喝維持消化道機能優酪乳)
告訴我們：
補充益生菌可以提高血清IL-4，IL-10(前兩者為抗發炎因子)和IFN-γ。
能提高IL-4的元素：
鎂、鋅、鈣、維生素A、維生素C、兒茶素、花青素(桑葚藍莓蔓越莓果汁)、茄紅素、薑黃素、黃酮類化合物(生物類黃酮、大豆異黃酮)、鞣花酸(桑葚藍莓蔓越莓果汁)
能提高IL-10的元素：
鎂、鈣、鋅、錳、硒、維生素A、維生素D、維生素E、兒茶素、花青素(桑葚藍莓蔓越莓果汁)、薑黃素、碘、茄紅素、黃酮類化合物(生物類黃酮、大豆異黃酮)、鞣花酸(桑葚藍莓蔓越莓果汁)
建議多喝維持消化道機能優酪乳
